ea0059cc10 | Featured Clinical Cases | SFEBES2018
Khoo Serena
, Lyons Greta
, McGowan Anne
, Gurnell Mark
, Oddy Susan
, Halsall David
, Chatterjee Krishna
, Moran Carla
Introduction: Familial dysalbuminemic hyperthyroxinemia (FDH) is characterized by artefactual hyperthyroxinemia caused by enhanced binding affinity of thyroxine to the mutant albumin. However little is known about how FDH affects the measurement of thyroid hormones, especially FT3, across many assay platforms.Methods: Forty-eight genetically confirmed FDH patients (R218H mutation) had FT4 and FT3 measured with 1-step (ADVIA CENTAUR®, Siem...